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Acetyl-L-carnitine has been shown to improve the number and function of mitochondria , which are cell components responsible for producing Adenosine Triphosphate (ATP), the primary energy currency of cells
10.1016/j.yexcr.2017.09.018 37 XieB.WuJ.LiY.WuX.ZengZ.ZhouC.et al (2019)
The citrate in excess of mitochondrial requirements is exported in the cytosol, converted into acetyl-CoA by ATP-citrate lyase (ACLY), and used for protein acetylation and lipogenesis
Patients should be counselled about common adverse effects including nausea, vomiting, diarrhoea, and constipation, which typically improve over time
Stable derivatives perform well anytime, while pure ascorbic acid might fare better at night to avoid light exposure
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