10.1016/j.pharmthera.2015.11.003 9 Carnet Le ProvostK.KeppO.KroemerG.BezuL
Iannone A, Natale P, Palmer SC, Nicolucci A, Rendina M, Giorgino F, et al
Nishino H et al
These factors include how often the injections are administered and the metabolism rate of the person
(2008) demonstrated that systemic administration of IGF-1 LR3 to dystrophic mdx mice (a model of Duchenne muscular dystrophy) significantly reduced susceptibility to contraction-mediated damage in extensor digitorum longus, soleus, and diaphragm muscles
The injections are relatively painless, using very thin needles, but the process requires some instruction and comfort with self-injection