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Selective glutamine metabolism inhibition in tumor cells improves antitumor T lymphocyte activity in triple-negative breast cancer

It is also an excretory route for cholesterol, bilirubin and many compounds that are too large, lipid- soluble or transporter-dependent for direct renal elimination

Currently, no FDA-approved assays are available for quantifying key RCD pathway activation markers (such as GSDMD-N fragment for pyroptosis, phosphorylated MLKL for necroptosis) in clinical practice, making accurate patient stratification difficult (178, 179)

10.1586/egh.11.87 34 CreedF.FernandesL.GuthrieE.PalmerS.RatcliffeJ.ReadN.et al (2003)

Taking medication by placing it under the tongue can be a lot less stressful for these individuals

The practical implication is simple but important