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Int J Environ Res Public Health

What the Numbers Show Average weight loss by timepoint: Week 12: 8.7% total body weight (19 pounds for 220-pound person) Week 24: 17.3% total body weight (38 pounds for 220-pound person) Week 36: 21.1% total body weight (46 pounds for 220-pound person) Week 48: 24.2% total body weight (53 pounds for 220-pound person) Data from Phase 2 clinical trial, 12mg dose cohort

Pharmacol Rev 2002;54:589-98

Taking two doses close together or doubling up on doses is not recommended and can increase side effects

This study has some limitations

Additionally, cumulative BrAC calculated using area under the curve (AUC) was reduced in the GLP-1RA group as compared to the control group ((F(1,14) = 9.36, p = 0.008, f = 0.82)