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Islets with centrally located bihormonal insulin + glucagon + cells were identified by visually identifying insulin + glucagon + cells located centrally to the 3 most peripheral cell layers
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These antihyperglycemic agents stimulate insulin secretion and inhibit the release of glucagon from pancreatic islets in a glucose-dependent manner
Sharma NM, Liu X, Llewellyn TL, Katsurada K, Patel KP
Independent HPLC + MS testing
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