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Article contents Abstract Introduction Urolithin A: sources, dosage and mechanism of action Spermidine: sources, dosage and mechanism of action Urolithin A and spermidine in autophagy and mitophagy: studies in vitro In vivo studies on urolithin A and spermidine Clinical studies on urolithin A and spermidine Conclusions Financial support Competing interests Authorship Consent for publication Declaration of generative AI and AI-assisted technologies in the writing process References Distinct roles of urolithin A and spermidine in mitophagy and autophagy: implications for dietary supplementation Published online by Cambridge University Press: 17 December 2025 Abstract Introduction Urolithin A: sources, dosage and mechanism of action Spermidine: sources, dosage and mechanism of action Urolithin A and spermidine in autophagy and mitophagy: studies in vitro In vivo studies on urolithin A and spermidine Clinical studies on urolithin A and spermidine Conclusions Financial support Competing interests Authorship Consent for publication Declaration of generative AI and AI-assisted technologies in the writing process References Abstract The increasing focus on longevity and cellular health has brought into the spotlight two key compounds, urolithin A (UroA) and spermidine, for their promising roles in autophagy and mitophagy

Grover PL, Sims P

Crosstalk of Signaling and Metabolism Mediated by the NAD(+)/NADH Redox State in Brain Cells

A Vitamin C skin brightening moisturiser seals in your serum while supporting your skin barrier

Uses for N-Acetyl Cysteine N-acetyl cysteine has a wide range of uses beyond its antioxidant properties

Vitiligo can be psychologically challenging for people who have it, and there is still limited research into the causes of vitiligo and treatments