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Cecal levels of Akkermansia muciniphila have been strongly correlated with physiological metrics including glycemia and insulinemia 89 , and Akkermansia has correlated negatively with obesity-related measures 90 and has been implicated in DIO prevention 91,92

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And critically, it acts on the hypothalamus to reduce appetite, creating powerful satiety signals that make people eat significantly less without feeling deprived

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