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Design, synthesis, and biological evaluation of triazolone derivatives as potent PPARalpha/delta dual agonists for the treatment of nonalcoholic steatohepatitis

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Fact: Some patients claim that injecting in the thigh or arm reduces gastrointestinal side effects like nausea compared to the abdomen

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It acts as a carrier molecule, shuttling fatty acid molecules across the mitochondrial membrane

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A livello periferico, lamilina rallenta lo svuotamento gastrico in modo complementare ma meccanicisticamente distinto dal GLP-1, sopprime la secrezione post-prandiale di glucagone (prevenendo liperglicemia) e favorisce il senso di pienezza gastrica

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"We definitely do see a slight change compared to the total population

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