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Modulation of CPT-1 may affect energy metabolism and food intake, and research is ongoing into the effects of both stimulation and inhibition of CPT-1 and in relation to obesity management [74]
Our patients deserve rigorous science to guide real-world decisions, and this is an important early step in a longer conversation
The latest dual-action GLP-1 analogue, tirzepatide , which also affects GIP receptors, was approved in the US in 2022 as the drug Mounjaro for the treatment of type 2 diabetes, and in 2023 as Zepbound for the treatment of obesity and excess weight, as well as obstructive sleep apnea syndrome in obese individuals
Dawood, R., Ismail, B., Alshaikh, A., & Alomar, A
More practically speaking, some of the higher-dose drugs, so tirzepatide
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