Your GP can: Assess your current weight, BMI, and metabolic health to determine clinical need Review existing treatment options that are currently licensed and available in the UK, which may include orlistat, naltrexone/bupropion (Mysimba), semaglutide 2.4 mg (Wegovy approved by the MHRA for weight management and subject to NICE guidance on eligibility, service setting, and treatment duration), and tirzepatide (Mounjaro check current MHRA and NICE status at the time of reading, as licensing and commissioning arrangements may have been updated) Discuss eligibility for NHS Tier 3 or Tier 4 specialist weight management services , in line with NICE guidance on obesity management, where pharmacotherapy is used as an adjunct to structured lifestyle intervention Signpost you to relevant clinical trials via the Be Part of Research portal or ClinicalTrials.gov if you wish to explore participation in retatrutide research It is important to approach information about investigational medicines with appropriate caution

Eli Lilly and Company, Lilly's oral GLP-1, orforglipron, demonstrated statistically significant efficacy results and a safety profile consistent with injectable GLP-1 medicines in successful Phase 3 trial, news release, April 17, 2025, [171]
Semaglutide, under the brand name Wegovy, can be used for weight loss
Compounded Semaglutide with Essential Vitamins Compounded Tirzepatide with Essential Vitamins Start Losing Weight Today
May your semaglutide stay clear, your storage stay cold, and your results stay consistent.
Unfortunately, these drugs are not meant to be combined