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Bloating is common during the first few weeks, especially at each dose increase
This happens most often when bacteriostatic water is too warm, when the lyophilised cake is older than six months, or when the vial is shaken instead of gently swirled
Crucial point: high quality human clinical trials that test CLA and L-carnitine together are scarce
Shaffer 2018)
The SUSTAIN trials reported DR worsening in some Semaglutide-treated patients, particularly those with pre-existing DR 23
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