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Annals of Internal Medicine, 178 (9), 12681278
LL6, the most promising novel small molecule kinase inhibitor obtained, induced apoptosis and suppressed the colony-forming capacities of various drug-resistant NSCLC cell lines, suppressed NSCLC cell migration, suppressed NSCLC xenograft tumor growth and Lewis lung carcinoma allograft tumor metastasis in mice, and markedly reduced the number and burden of lung tumors in KrasG12D/+ transgenic mice, with low toxicity (54)
Son herramientas farmacolgicas potentes que han cambiado la historia del tratamiento de la diabetes y la obesidad
[PMID: 3118868] PubMed record related to this compound for laboratory literature review
2022;9:e8974 28
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