retatrutide weight loss clinical trial retatrutide Triple hormone receptor agonist for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a Retatrutide: FDA approval time, trial

doi: 10.1038/s41586-025-09588-6 238 MichaudM.BalardyL.MoulisG.GaudinC.PeyrotC.VellasB.et al

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For a closer look at common digestive effects, read about common GLP-1 side effects

This mostly modulates GLP-1 homeostasis through the action of a GLP-1 receptor agonist [31]

[3] [4] A higher-dose formulation of semaglutide (marketed as Wegovy) is separately licensed for weight management in adults with obesity or overweight with weight-related comorbidities, according to NICE criteria (TA875)