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Morbid obesity in PWS leads to increased risk of cardiopulmonary compromise, type 2 diabetes mellitus (DM), chronic leg edema, premature cardiovascular disease, and death [1,2]

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Interestingly, the hierarchical clustering analysis of DAPs in five comparison groups showed that DAPs of T2/T1, T3/T1 (Additional file 5: Table S5), T4/T1, T4/T2 (Additional file 6: Table S6) and T4/T3 had different expression patterns (Fig

The oxidation of TMABA to -BB is a key step, as it forms the direct precursor to L-carnitine

Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia