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Estrategias de manejo: Iniciar con la dosis ms baja y aumentar gradualmente segn lo prescrito Administrar la inyeccin en un da consistente de la semana, independientemente de las comidas Rotar los sitios de inyeccin (abdomen, muslo o parte superior del brazo) Mantener una hidratacin adecuada, especialmente si presenta diarrea o vmitos Mantener un registro de sntomas para discutir con su mdico No suspender el medicamento sin consultar a su proveedor de salud La mayora de los pacientes experimentan una mejora significativa de estos sntomas despus de 4-8 semanas de tratamiento continuo

doi: 10.1038/s41568-021-00417-2 27 GernandA

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