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Gastrointestinal and mucosal biology
Human efficacy data are limited
Severe reactions are rare, and any discomfort usually dissipates after a few minutes
The glucose dependent insulinotropic polypeptide response to oral glucose and mixed meals is increased in patients with type 2 (non-insulin-dependent) diabetes mellitus
Additionally, the identification of susceptible populations and critical exposure windows requires more sophisticated biomarker approaches and personalized risk assessment tools
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