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However, the mechanisms by which SGLT2 inhibitors exert these benefits beyond glucose-lowering are not fully understood

Any disruption to gastric physiology or transit time could theoretically affect this intricate absorption pathway

33 In a randomized, double-blind, placebo-controlled trial involving patients with MASH, treatment with NGM282 (an engineered FGF19 analog) for 12 weeks led to rapid and significant reductions in liver fat content, ALT, AST, and serum markers of fibrogenesis

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By 2024, the number of diabetes patients in China had risen to 148 million

doi: 10.1016/j.semcdb.2012.12.002 18 DoyleMEPremathilakeHUYaoQMazucantiCHEganJM