A 2-way-ANOVA followed by Sidaks multiple comparison test assessed both NAC-treatment and IPTB-severity factors for each blood compartment and metabolite, while the non-parametric Kruskal-Wallis test was used to assess metabolite differences between blood compartments in each IPTB and treatment subgroup, followed by the Wilcoxon matched-pairs signed-rank test for multiple comparisons between maternal and paired-cord blood samples
Yoshio Y, Rintaro S, Shunji S
Koreans don't even care that much, she said
Over the years, methods have been refined into the most commonly used protocol today, which uses an acid/ethanol precipitation (to disrupt the IGF-1/IGFBP complex) followed by the addition of insulin-like growth factor-2 (IGF-2) to prevent the reformation of the IGF/IGFBP complex
Finally, the majority of mechanistic insights are derived from preclinical models, and the translation of these pathways to human pathophysiology remains incompletely elucidated
Zhu, J., Wu, Y., Tang, Q., Leng, Y