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The idea of using a metric such as the clinically meaningful change can be applied to assess whether the outcome is not only statistically relevant, but would be meaningful to a person with a particular disease

Interest in these drugs for weight loss has risen over the past several years, and the appeal has yet to wane

Originally developed for type 2 diabetes, GLP-1 receptor agonists, like semaglutide, work by stimulating insulin release, slowing digestion, and signaling fullness in the brain

Cloudy or gel-like solution: treat it as failed, not ready for accurate research

GLP-1 receptor agonists (short for glucagon-like peptide 1) are a class of medications that mimic a natural hormone in the body

Outcomes 16 , e009078 (2023)