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This functional reversion is partly attributed to a decrease in PGE2 levels, a mediator of MDSC-induced immune suppression

Also, glutathione reduces cystine and cysteine-mixed disulphides to cysteine, thus making cysteine available for protein synthesis

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In cells that survive treatment, 5FU promotes a sustained increase in mitochondrial content over 72 h, as shown by changes in levels of nonyl-acridine orange (NAO) staining (Fig

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