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References Savarese G, Becher PM, Lund LH, Seferovic P, Rosano GMC, Coats AJS (2023) Global burden of heart failure: a comprehensive and updated review of epidemiology

Variability in assay platforms, sensitivity, and patient heterogeneity further complicates cross-study comparisons

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The results confirmed their expectations, but expression was at different levels in different organs

Theoretical bioavailability may be higher than oral tablets, but real-world effectiveness data for sublingual GLP-1 delivery remains limited

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