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These effects remain under active investigation in humans, and the evidence base is not yet definitive
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The compounds primary action involves modulating nitric oxide system activity, which helps stabilize the balance between vasodilation and vasoconstriction, especially in ischemic conditions
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The results of the SURE-PD trial revealed that treatment with inosine for up to 24 months was clinically safe and well-tolerated at doses that elevated serum UA concentrations from a mean of 4.5 mg/dL to 6.17.0 and 7.18.0 mg/dL [104]