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6.5 TMAO and metabolic associated fatty liver disease MAFLD, closely linked to metabolic syndrome, T2DM, and obesity, associates with elevated TMAO

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Rybelsus is the first in this class to come as a once-daily pill, offering a convenient option for those who prefer not to use injections

Actually, silicone sheets are also very effective, but I find patients are more likely to stick with the gel because it is much easier to use

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Additionally, UK supply constraints mean the medication is prioritised for people with diabetes