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In an additional study group, patients received a triplet combination: semaglutide, anti-myostatin, and anti-activin A (garetosmab)
You can read the full article at Semaglutide induces weight loss in subjects with type 2 diabetes regardless of baseline BMI or gastrointestinal adverse events in the SUSTAIN 1 to 5 trials In the SUSTAIN 1 to 5 studies, semaglutide was found to cause more weight loss and HbA1c level reductions than other drugs, although the underlying mechanisms causing this weight loss were not previously known
This medication has a 94% similarity to human GLP-1, making it highly effective at binding to and activating GLP-1 receptors [3]