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Januvia for type 2 diabetes Januvia is FDA-approved to treat high blood sugar caused by type 2 diabetes in adults, along with diet and exercise

Unlike metformin, which has a well-established association with vitamin B12 malabsorption through interference with calcium-dependent B12-intrinsic factor complex absorption in the terminal ileum, there is no official link between GLP-1 receptor agonists and direct B12 depletion

For patients with type 2 diabetes, other medication classes with fewer gastrointestinal effects might be preferable, such as SGLT-2 inhibitors or DPP-4 inhibitors

2.3 Statistical analysis The clinical profile, such as age, sex, primary data source, outcomes, reported year, source region, and indication, were detailed individually for each GLP-1 RAs

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15: 100181 Karagounis L, Hawley J