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They can also provide energy substances such as lactic acid to neurons through the metabolism of glial cells (Falkowska et al., 2015) and in the AD brain can reduce the production of A to reduce toxicity (Timmer et al., 2010), inhibit certain inflammatory factors, and increase resistance to oxidative stress (Jia et al., 2015)

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others stay on a lower maintenance dose

Grasset, E., Puel, A., Charpentier, J., Collet, X., Christensen, J

In this study, the highest versus lowest quartile of urinary potassium excretion (mid-values, 3,043 mg/day versus 1,484 mg/day) was associated with a 62% lower risk of hypertension (37)

Therefore, at steady state, the variability in total and within-subject variability in exposure is reduced compared with after a single dose