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In the noncanonical pathway, NLRP3 inflammasome activation is induced by lipopolysaccharide (LPS) internalization into the cytosol by transfection or infection (Santos et al., 2018), which can be recognized by caspase-11 (the mouse homolog of human caspase-4/5)

Relative to Day 1 fed animals, the average volume and number of DHS-3::GFP positive lipid droplets after a 24-h fast were reduced by 84% and 65%, respectively, as determined by fluorescence microscopy (Fig

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