Weight loss effectiveness: what the clinical trials show Numbers matter more than marketing
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doi: 10.1038/s41467-019-10386-8 54 WeiQ.HariharanV.HuangH
Saxenda: nausea, diarrhea, constipation, vomiting, injection site reactions, headache, low blood sugar, upset stomach, fatigue, dizziness, abdominal pain, increased lipase (a digestive enzyme), upper abdominal pain, fever, and gastroenteritis (inflammation of the stomach and intestines)
In fact, research shows that fiber stimulates the release of GLP-1 to reduce hunger and appetite, which may be one reason why fiber can lead to weight loss
Addressing its poor solubility, rapid metabolism, and low membrane permeability through delivery systems including nanocarriers may prove beneficial, but research is limited