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In an opinion published in the BMJ on July 21, 2025, Ellen Fallows noted the risks of prescribing GLP-1 medications to patients who already consume nutrient-poor diets, highlighting that malnutrition cases are already being reported in the U.S

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The specific reactions users report most often: Compare this to actual GLP-1 receptor agonists, where nausea affects 20 to 44% of users, vomiting 5 to 24%, and constipation 12 to 24% across the STEP 1 and SURMOUNT-1 trial programs

Signs of an allergic reaction, though rare, constitute a medical emergency

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