Although many transporter-utilizing (pro)drugs and nanocarriers have been developed to improve the uptake of drugs to the brain, their success rate of translation from preclinical development to humans is negligible
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Thng qua c ch, bng cch can thip vo qu trnh chuyn ha v ngn nga hot ng ca enzyme tyrosinase, gip lm o ngc tin trnh tng hp sc t melanin sng thay v tng hp cc sc t melanin ti, Glutathione h tr lm trng da ton thn, tng cng to ra sc t melanin sng v ngn chn to ra hc t melanin (melanin en), kt qu l da dn trng sng v u mu hn
Pre-clinical and mechanistic studies on cognitive disorders, substance-use disorders, psychotic disorders, mood and anxiety disorders, and eating disorders (Supplementary Table 5
Moi et al, 1994)
Activation of AMPA receptors mediates the antidepressant action of deep brain stimulation of the infralimbic prefrontal cortex