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Typical daily range: 300500 mcg once daily, often fasted or pre-workout, raised gradually over an 816 week course

In their separate Phase 2 trials, retatrutide monotherapy showed larger weight loss (~24.2% at 48 weeks, 12 mg) than standalone cagrilintide (~10.8% at 26 weeks, 4.5 mg), and indirect network meta-analyses rank retatrutide highly

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Additionally, it has shown potential benefits for hair appearance, reducing hair loss, and even neuroprotective effects, such as mitigating amyloid plaque formation

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