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In a chronic study testing liraglutide, APP/PS1 mice were treated for 8 months starting at 2 months of age before the amyloid pathology developed
95% CI, 1.26-1.56), but shorter duration (=26 weeks) of treatment was not (RR 0.79)
It is usually administered once a week by injection hence the term weight loss injection
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Carlsson, Carlsson, Jacobson)
Some patients experience some initial worsening (20-30%), and in some cases it can be severe, requiring urgent dose reduction and addition of oral corticosteroids
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