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Average Weight Loss in the Orforglipron phase 3 ATTAIN-1 Trial Across the 72-week study period, participants: Lost up to 15% of their body weight at the highest dose At 36 mg: 54.6% lost 10%, 36.0% lost 15%, 18.4% lost 20% body weight (all higher than placebo)

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These use either gel packs that are replaced daily or battery-powered active cooling systems that maintain precise temperatures

10.1016/j.autneu.2024.103198 287 LiuX.LiY.GuM.XuT.WangC.ChangP

These may indicate a need for treatment adjustment or evaluation of underlying conditions

A licensed provider determines whether compounded tirzepatide is appropriate for you