PlexusDx streamlines this entire process by pairing telehealth consultations with compounded GLP-1 medications from licensed pharmacies
The population-level signal, however, is hard to dismiss
In September, the government of Quebec announced a pilot project to determine whether it should cover the use of GLP-1 drugs to treat obesity and not just diabetes
The OR for achieving a weight loss of at least 5% with tirzepatide 5 mg, 10 mg and 15 mg (vs GLP-1 RAs) was, respectively, 1.96 (95% CI 1.01, 3.80 [ I 2 61%]), 4.79 (95% CI 1.95, 11.73 [ I 2 74%]) and 4.57 (95% CI 3.38, 6.18 [ I 2 0%]) (ESM Table 2)
Early study revealed a direct modulation of GLP-1R on the electrophysiological activities of orexinergic neurons in the lateral hypothalamus
For many people, the shift is not only physical