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The mortality rates in severe sepsis were almost 41% in Europe against around 28 We aim to investigate the effects of high dose l-carnitine supplementation on inflammatory mediators, oxidative stress, clinical outcomes, and the rate of mortality in ICU septic patients

Those with inadequate GLP-1 response, cardiovascular risk factors, or specific metabolic patterns may see greater benefit from tirzepatide's dual mechanism

By activating GLP-1 receptors, it slows gastric emptying and reduces appetite, leading to lower food intake and weight loss

Additionally, patients taking immunosuppressive medications may have altered responses to infections, and any medication causing significant gastrointestinal symptoms could affect absorption of oral immunosuppressants

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