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A second direction of the interrelationship between psoriasis and obesity indicates that patients with psoriasis have elevated levels of inflammatory cytokines, particularly TNF-, which can lead to metabolic abnormalities, including insulin resistance, and may consequently lead to the development of obesity (211)
All treatments were delivered in the presence of phenol red-free DMEM medium (Sigma)
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Acta Physiol Plant 36, 8599
[4] A fourth route, intranasal delivery, has been explored in the context of neurological applications on the premise that the nasal mucosa provides a direct pathway to the central nervous system via the olfactory nerve