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Glucagon receptor activation drives hepatic fat oxidation (the liver burns stored fat for energy), increases resting energy expenditure by an estimated 150-200 kcal per day based on published metabolic data, and reduces hepatic lipid accumulation
A deficiency may cause dry, flaky, and reddened skin
use for weight management is off-label and must be discussed with your prescriber
Tipa et al., 2024)
"Retatrutide in Patients with NAFLD: A Randomized Phase 2 Trial." Hepatology/AASLD.(Confirms that lower doses are highly effective for metabolic/liver health)
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