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The usual starting dose, for both weight loss and diabetes, is 0.25 mg
Proposed pathways for OTA bioactivation and reactive intermediates include (i) an aryl radical formed by reductive dechlorination, (ii) a phenoxyradical formed by one-electron oxidation, and (iii) OTQ formed from OTA as a result of oxidation mediated by peroxidases or cytochrome P450 (CYPs) (Tozlovanu et al
Medical supervision remains essential throughout treatment, especially when adjusting doses or experiencing persistent symptoms