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On average, tirzepatide has been shown in research to lead to a greater amount of weight loss : People with obesity in clinical trials for tirzepatide lost, on average, 20% of their body weight at week 72 (and about 7 inches off their waistlines), compared with about 14% of their body weight (and about 5 inches off their waistlines) with semaglutide

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It can be taken as an oral pill or injection, and its available from gray-market sellers online

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They are different categories with different mechanisms, different regulatory classifications, and different use cases