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When ROCK is inhibited with Y-27632, it causes a redistribution of F-actin, leading to decreased nuclear localization of YAP and reduced expression of Cgtf and Cyr61
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Sirtuins, particularly SIRT1 and SIRT3, protect cells from oxidative stress by increasing the activity of antioxidant enzymes, including superoxide dismutase 2 (SOD2) and CAT (127, 131, 132)
Kojic Acid: This natural ingredient is derived from various types of fungi or through fermentation
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