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Missense variants involve substituting a single amino acid, resulting in a protein with reduced or different functionality
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Some Phase 3 trial sites are in Asia (REDEFINE 5, REDEFINE 6) but no regulatory approvals have been announced as of June 2026
Yes, several manufacturers specialize in OEM/ODM services for vitamin B12 supplements
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However, neither compound is MHRA-approved for medical or therapeutic use in the UK
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