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Practical Interpretation The mechanistic plausibility (NNMT NAD SIRT1/PGC-1 BMR & fat oxidation) is strong and consistent across preclinical models

Choosing between them depends on specific health goals, particularly regarding cognitive function and brain health, where ALC may offer additional benefits

Sometimes high doses can cause side effects like gastrointestinal problems or lightening of skin, so moderation is important

This dual functionality establishes it as a complex yet promising target for cancer treatment (216)

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