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Most common (especially in first 4-8 weeks): Nausea Early fullness/satiety Constipation Mild reflux or burping Less common but important: Severe nausea preventing adequate eating or drinking Gallbladder issues (rapid weight loss increases gallstone risk) Pancreatitis (rare, more common with high triglycerides or gallstone history) Dehydration The side effect no one mentions: Undereating
many remain on a stable maintenance dose after reaching their target
In 2023, the FDA approved tirzepatide for weight loss under the brand name Zepbound
If your dose calculates to 16.7 units, round to 17 units (rounding up by 0.3 units delivers an extra 0.015 mg at 5 mg/mL, clinically irrelevant)
Product Specifications Semaglutide Quality Documentation and Lot Testing HPLC Purity Verification (99%) Reverse-phase high-performance liquid chromatography is used to quantify chromatographic purity for each production lot
Semaglutide (Ozempic, Wegovy) is a GLP-1 receptor agonist that must be refrigerated at 36F to 46F (2C to 8C) before first use to maintain its effectiveness
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