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Starting at a low dose of 0.25 mg in the first week is a crucial step to minimize potential gastrointestinal side effects that many patients experience when beginning treatment with semaglutide GLP-1
Gutzwiller JP, Tschopp S, Bock A, Zehnder CE, Huber AR, Kreyenbuehl M, Gutmann H, Drewe J, Henzen C, Goeke B, Beglinger C: Glucagon-like peptide 1 induces natriuresis in healthy subjects and in insulin-resistant obese men
Another report also showed that GLP-2 alleviates the development of colitis through reducing the pro-inflammatory cytokines in IL-10-deficient mouse model
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