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The dual-action mechanism of semaglutide helps to control appetite by delaying stomach emptying and creating a feeling of fullness, leading to reduced food intake

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Retrieved 27 July 2017

On the other hand, administration of tirzepatide at a dose of 70 nmol/kg/day, resulted in a significant weight loss associated with shorter femur compared to saline-treated diabetic mice, but no evident alterations of bone microarchitecture or strength [69]

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