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PT-141 (bremelanotide, Vyleesi) is approved by the FDA only for acquired, generalized hypoactive sexual desire disorder in premenopausal women, and its approved indication explicitly excludes low desire due to a co-existing psychiatric condition (such as depression) or the effects of a medication (such as an antidepressant)

Using a GLP-1 vial beyond the recommended use period may increase the risk of contamination and may reduce medication effectiveness

doi:10.1146/annurev.nutr.24.012003.132440

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10.1056/NEJM199807233390404

This is the more commonly recommended option, and for good reason