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It plays a crucial role in neutralizing free radicals, detoxifying the liver, and supporting the immune system

This leads to an advance stage of atherogenesis in which plaques contain lipids, cholesterol, macrophages and altered myocytes 5

Additionally, dietary factors can contribute to this effect

Since 10 mg of tirzepatide significantly improved glycemic control after switching from 1.0 mg of semaglutide, early escalation to 10 mg may be beneficial for patients who respond inadequately to semaglutide