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Alternative medication classes should be considered if GLP-1 therapy proves intolerable: SGLT2 inhibitors (such as dapagliflozin, empagliflozin) for type 2 diabetes, which work via a completely different mechanism and rarely cause gastrointestinal side effects DPP-4 inhibitors (such as sitagliptin, linagliptin), which enhance endogenous GLP-1 activity more gently Metformin remains first-line for type 2 diabetes, though it can also cause gastrointestinal side effects Orlistat for weight management, though this also has gastrointestinal side effects of a different nature For weight management specifically, NICE recommends a comprehensive approach including dietary modification, increased physical activity, and behavioural interventions, with or without pharmacotherapy
A urinary tract infection (UTI) can cause a color or odor change
[Campanulaceae], which exhibits many pharmacological activities, such as anti-inflammatory, anti-cancer, immune modulator, and anti-oxidant activities (Wang B
The active ingredient, semaglutide, is used in the now-famous Ozempic and Wegovy medications for diabetes and weight loss
Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P
Bipolar disorder is a chronic psychiatric disease accompanied by unpredictable periods of depression and mania, cognitive decline, and inflammatory states [230]
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