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Lee MS, Bui HD, Kim SJ, Lee JB, Yoo HS
In addition to boosting GLP-1, the GLP-1/GIP agonist tirzepatide (Zepbound) mimics the hormone gastric inhibitory polypeptide (GIP), which has similar effects to those of GLP-1
Should you get GLP-1s through the Bridge program
Where estrogen helps maintain the existing architecture of synaptic networks, GLP-1 signaling supports the biological machinery that allows those networks to adapt, strengthen, and repair
Another potential issue is that beneficiaries who participate in the short-term program will need to be enrolled in a Part D plan that participates in the longer-term demonstration, called the BALANCE Model, to continue accessing Medicare coverage of GLP-1s for obesity starting in 2027
A clinician-guided evaluation is the safer path
