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Pharmacology of dimethyl sulfoxide in cardiac and CNS damage

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Figure 1 4.1 Macrophage fatty acid metabolic disorders potentiate MSU crystal-induced inflammation Numerous studies have shown that the inflammatory factor interleukin-1 beta (IL-1) is essential for MSU crystal-driven inflammation and is released, in place of infiltrating neutrophils or monocytes, from the resident macrophages in the initial stage of GA (38, 39)

Cross talk between eIF2alpha and eEF2 phosphorylation pathways optimizes translational arrest in response to oxidative